Altered mitochondrial function and genome frequency post exposure to γ-radiation and bystander factors

Authors

Fiona Lyng, Technological University DublinFollow
Sharon Nugent,, Technological University DublinFollow
Carmel E. Mothersill,, McMaster University, Ontario, Canada.Follow
Colin Seymour, McMaster University, Ontario, Canada.
Brendan McClean,, St. Luke’s Hospital, Dublin.
James E. J. Murphy, Institute of Technology Sligo,

Document Type

Article

Rights

Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence

Disciplines

Biophysics

Publication Details

Int J Radiat Biol. 2010 Oct;86(10):829-41. doi: 10.3109/09553002.2010.486019.

Abstract

PURPOSE:

To further evaluate irregular mitochondrial function and mitochondrial genome damage induced by direct γ-irradiation and bystander factors in human keratinocyte (HPV-G) epithelial cells and hamster ovarian fibroblast (CHO-K1) cells. This is as a follow-up to our recent reports of γ-irradiation-induced loss of mitochondrial function and mitochondrial DNA (mtDNA) damage.

DOI

https://doi.org/10.3109/09553002

Recommended Citation

Murphy, E.J. et al. (2010) Int J Radiat Biol.2010 Oct;86(10):829-41. doi: 10.3109/09553002.2010.486019.

Funder

Department of Education & Science