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1.4 CHEMICAL SCIENCES
This paper details a miniaturised, solid state ion-selective electrode selective for diclofenac. The sensor comprises a novel ionic liquid electroactive material – an imidazolium–diclofenac ion associate. The ion associate is present in a plasticised poly(vinyl chloride) (PVC) membrane on planar carbon electrodes, with an intermediate poly(3,4-ethylenedioxythiophene) layer. The sensitivity and selectivity of the sensor were determined using chronopotentiometric methods. In response to diclofenac, a slope of −53.3 ± 3.6 mV/dec was observed. A limit of detection of 2.90 × 10−3 g L−1 is reported, with a linear range of 3.18 × 10−3 g L−1 to 3.18 g L−1. The sensors show good selectivity towards diclofenac against pertinent interferent molecules, with a response time of <15 s.
Brennan, E., Futvoie, P., Cassidy, J. & Schazmann, B. (2017). An ionic liquid based sensor for diclofenac determination in water.International Journal of Environmental Analytical Chemistry, 97(6),pp. 588-596. doi:10.1080/03067319.2017.1333607