Document Type

Article

Rights

This item is available under a Creative Commons License for non-commercial use only

Disciplines

Inorganic and nuclear chemistry

Publication Details

Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2000, Vol. 36, pp.179-189.

Access publisher website at http://www.springer.com/?SGWID=0-102-24-0-0&searchType=EASY_CDA&queryText=Journal+of+Inclusion+Phenomena+and+Macrocyclic+Chemistry

Abstract

Enantioselectivity towards several amino acids by metallo-6A-deoxy-6A-hydroxyethylamino-β-cyclodextrins (metallo- β CDea’s) was investigated by potentiometric titration of the various amino acid/metallo- β CDea systems with NaOH solution. It was shown that the cyclodextrin derivative is capable of distinguishing between enantiomers of amino acid species in the presence of certain metal ions (Co, Ni, Cu and Zn). Ni- β CDea complexes show the most enantioselectivity,whereas for Cu and Co2C-_CDea complexes less selectivity is observed. As expected, Zn- β CDea complexes exhibit no enantioselectivity. Stability and selectivity, however, do not go hand in hand, since the most stable complexes are formed with Cu2C. Several factors play a role in determining stability and selectivity in binary and ternary complexes and further study is required to gain a more comprehensive understanding of these.

Included in

Chemistry Commons

Share

COinS