Document Type

Article

Rights

This item is available under a Creative Commons License for non-commercial use only

Publication Details

Journal: Heat and Mass Transfer

Article title: A mathematical analysis of drug dissolution in the USP flow through apparatus DOI: 10.1007/s00231-017-2151-z Editorial manuscript number:HAMT-D-17-00155.1
Date of acceptance: 24th August 2017

Date of Publication: 02th October 2017

Abstract

This paper applies boundary layer theory to the process of drug dissolution in the USP (United States Pharmacopeia) Flow Through Apparatus. The mass transfer rate from the vertical planar surface of a compact within the device is examined. The theoretical results obtained are then compared with those of experiment. The paper also examines the effect on the dissolution process caused by the interaction between natural and forced convection within the apparatus and the introduction of additional boundaries.

DOI

https://doi.org/10.1007/s00231-017-2151-z

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