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<title>Conference Papers</title>
<copyright>Copyright (c) 2013 Dublin Institute of Technology All rights reserved.</copyright>
<link>http://arrow.dit.ie/scschphycon</link>
<description>Recent documents in Conference Papers</description>
<language>en-us</language>
<lastBuildDate>Wed, 29 May 2013 13:35:54 PDT</lastBuildDate>
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<title>One Student One Family and the Mozambique Eyecare Project, the Interaction Between Optometry Students and the Community in Nampula, Mozambique</title>
<link>http://arrow.dit.ie/scschphycon/14</link>
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<pubDate>Wed, 13 Mar 2013 08:27:11 PDT</pubDate>
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	<p>This paper aims to explore the successes and challenges of the One Student One Family programme within the context of the Mozambique Eyecare Project.</p>

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<author>Stephen J. Thompson</author>


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<title>Primary School Vision Screening Involving Teachers in Nampula, Mozambique.</title>
<link>http://arrow.dit.ie/scschphycon/13</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/13</guid>
<pubDate>Fri, 27 Jul 2012 06:16:56 PDT</pubDate>
<description>
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	<p><strong>Purpose</strong></p>
<p>There is no plan for a national child eye care programme or existing human resource infrastructure to address the immediate challenge of child eye health in Mozambique. Furthermore, the prevalence and incidence of refractive error, visual impairment (VI) and child blindness (CB) in Mozambique is unknown. VI and CB have devastating personal, developmental, economic and other implications for the child, the family, the community and indeed, the nation. This study aims to design, implement and evaluate a school based paediatric vision screening service, to identify those in need of eye health services, among Mozambique’s 11,561,000 children.</p>
<p><strong>Methods</strong></p>
<p>Primary School Screening took place in three schools in Nampula, Mozambique in September 2010 and March 2011. The children’s vision was screened by an optometry student, optometrist or teacher with a Log MAR 0.3 line at 4 Meters. Ophthalmoscopy was performed on all children. Children who failed to read all 5 letters monocularly had their visual acuity examined on a standard Log Mar chart. If they failed to see the 0.3 line on the standard chart they had a full refraction on site. Children who required refraction were refracted on site. Those needing ophthalmological assessment were referred to Nampula Central Hospital, Ophthalmology Unit.</p>
<p><strong>Results</strong></p>
<p>These studies found that there is a cohort of students attending school in Nampula who are in need of eyecare service provision. Refractive Error was present among this population tested in these studies but none of the children observed wore spectacles.The training received by these teachers was very brief but teachers appear to have an adequate level of education and interest to undertake vision screening in children. The ideal teacher profile for Vision Officers within schools is trainee teachers who can be taught the basics of vision screening and eye health through their existing studies.</p>
<p>The results of this study will inform a regional pilot teacher screening project for Nampula, which will include the addition of “Vision Screening” to teacher training modules at Pedagogical Universities in Nampula, Mozambique, as part of a plan to develop a national child eye care programme for Mozambique.</p>

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<author>Aoife Phelan</author>


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<title>Primary School Vision Screening Involving Teachers in Nampula, Mozambique</title>
<link>http://arrow.dit.ie/scschphycon/12</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/12</guid>
<pubDate>Fri, 06 Jul 2012 08:44:19 PDT</pubDate>
<description>
	<![CDATA[
	<p>Purpose: There is no plan for a national child eye care programme or existing human resource infrastructure to address the immediate challenge of child eye health in Mozambique.This study aims to design, implement and evaluate a school based pediatric vision screening service, to identify those in need of eye care services, among Mozambique’s 11,561,000 children.</p>
<p>Methods: Primary School Screening took place in three schools in Nampula, Mozambique in September 2010 and March 2011. The children’s vision was screened by an optometry student, optometrist or teacher with Log MAR ETDRS letters at 4 Meters. Ophthalmoscopy was performed on all children by qualified optometrists. Children requiring refraction were refracted on site, those needing ophthalmological assessment were referred to the ophthalmologist in Nampula Central Hospital.</p>
<p>Results: 770 children were screened in total. The ocular abnormality detection rate was 10.65%, and included 7.40% of children requiring spectacle provision, and the remaining 3.25% requiring referral to the Ophthalmology Unit. The distribution of myopia, hyperopia and astigmatism among children provided spectacles was 28.57%, 12.5% and 58.93% respectively, and overall prevalence in the study sample was 2.21%, 0.91% and 4.29% respectively. Referrals for ocular health abnormalities included, cataract (26.92%), ptosis (23.08%), glaucoma (15.38%). All teachers interviewed are eager to participate in a vision screening programme. Two Primary School Teachers were trained in vision screening. Teachers scored 100% case detection agreement with optometrists and student optometrists, with no noted false positive or false negative referrals. Conclusions: Teachers appear to have an adequate level of education and interest to undertake vision screening in children. This study will inform a regional pilot teacher screening project for Nampula, which will include the addition of “Vision Screening” to teacher training modules at Universidade Pedagogica, Nampula, as part of a plan to develop a national child eye care programme for Mozambique.</p>

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<author>Aoife Phelan et al.</author>


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<title>Optimising Design Parameters of Enzyme-Channelling Biosensors</title>
<link>http://arrow.dit.ie/scschphycon/11</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/11</guid>
<pubDate>Fri, 25 May 2012 10:23:59 PDT</pubDate>
<description>
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	<p>Two mathematical models for an electrochemical biosensor are proposed and compared with a view to determining the ratio of two immobilized enzymes which maximizes the amperometric signal amplitude.</p>

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<author>Dana Mackey et al.</author>


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<title>Programme of Strategic Cooperation between Irish Aid and Higher Education, Research and Non-Governmental Institutions</title>
<link>http://arrow.dit.ie/scschphycon/9</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/9</guid>
<pubDate>Thu, 20 Jan 2011 08:02:31 PST</pubDate>
<description>
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	<p>BACKGROUND It is increasingly recognised that a well-functioning higher education system is a necessary condition for economic and social development. The sector however needs to considerably strengthen its capacity to make an effective contribution to poverty reduction. The Irish Aid funded Programme of Strategic cooperation is designed to facilitate the systematic integration and expansion of education and research institute engagement in development cooperation.   OBJECTIVES This ambitious North-South programme aims to achieve capacity strengthening, through a medium term effort to invest in people, systems and knowledge building. The longer term consolidation of this collaboration aims to foster academic and non-academic leadership in development cooperation for eye care.   METHODS The Mozambique Eyecare Project (MEP), a strategic collaboration between Dublin Institute of Technology, University of Ulster, Universidade Lúrio and the International Centre for Eyecare Education have successfully secured Programme funding, and brings eye care to the forefront of Irish Aid’s development agenda.  RESULTS The MEP continues to: • initiate collaborative research • enhance teaching and learning across institutions • establish a flourishing cross-institutional network • generate specialist knowledge, research expertise, increased awareness and critical engagement in development cooperation.   These successes have already driven policy change in Mozambique including the recognition of a new professional cadre for eye care service delivery.  DISCUSSION The higher education sector is seen as a key organ in strengthening governance, research generation and knowledge development, and creating space for independent analysis of development issues to address public sector needs. In funding this initiative, Irish Aid provide formal recognition that poor vision is an indicator of vulnerability, a constraint to sustainable livelihood development and education and more generally implicated in health and poverty complexes. This represents a significant broadening of Irish Aid’s development agenda for Mozambique.</p>

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<author>James Loughman</author>


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<title>Macular Pigment and its Correlation with Colour Vision and SWAP Perimetry</title>
<link>http://arrow.dit.ie/scschphycon/8</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/8</guid>
<pubDate>Thu, 20 Jan 2011 07:57:48 PST</pubDate>
<description>
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	<p>Purpose To investigate the effects of macular pigment optical density (MPOD) on colour vision and colour modulated visual fields using short-wavelength automated perimetry (SWAP). Methods Macular pigment (MP) spatial profile was measured using customised heterochromatic flicker photometry (cHFP) on 51 normal subjects. Colour vision was assessed using the Oculus anomaloscope [Moreland equation (AME)] and Farnsworth-Munsell 100-Hue (FM) with optimum confusion axes. A custom designed program on the Humphrey automated perimeter, was used to determine SWAP thresholds at the fovea, and at each degree of retinal eccentricity for the central five degrees. A 440nm Goldmann V stimulus presented on a 100cd/m2 bleaching background was used to isolate the short wave sensitive pathway. Results While inter-relationships were evident between AME, FM and SWAP, only one colour vision measure (on FM) correlated with MPOD (r=.302, p= 0.03). At similar degrees of eccentricity, SWAP was inversely and statistically significantly correlated with MPOD (e.g. 1-degree retinal eccentricity: r = -0.198, p = 0.047; 3 degrees retinal eccentricity r = -0.290, p = 0.03). Conclusion Colour vision, even using sensitive tests targeting blue-yellow and blue-green confusion is surprisingly independent of MPOD, while SWAP sensitivity is reduced with increased MPOD. We hypothesize that this is due to long-term adaptation of the retinal blue-yellow pathway to prevailing MPOD in normal subjects, this adaptation being upset by short-term chromatic adaptation in SWAP.</p>

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<author>James Loughman et al.</author>


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<title>Macular Pigment Levels Increase Following Blue-light Filtering Intraocular Lens Implantation</title>
<link>http://arrow.dit.ie/scschphycon/7</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/7</guid>
<pubDate>Thu, 20 Jan 2011 07:57:47 PST</pubDate>
<description>
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	<p>Purpose:Photo-oxidative stress is believed to play a role in AMD pathogenesis. Macular pigment (MP), consisting of lutein (L), zeaxanthin (Z) and meso-Z, has a max absorption at 460nm and protects the retina from photo-oxidative injury. We investigated whether the blue light filtering properties of the Alcon AcrySof Natural intraocular lens (ANIOL) implanted during cataract surgery impacts on MP optical density (MPOD). Methods:44 patients scheduled for cataract surgery were recruited. All patients had pre-op best corrected visual acuity (BCVA) of at least 0.5logMAR in the study eye. Patients were randomised to have either the standard Alcon AcrySof 3-piece acrylic intraocular lens (AIOL) or the ANIOL. Spatial profile of MPOD was measured by customised heterochromatic flicker photometry (cHFP) 1 week pre-op and 1 week post-op, and at 3, 6 and 12 months post-op. Serum concentrations of L and Z were measured at each visit. Results:There was a significant positive correlation between MPOD values at 0.25deg recorded 1 week pre- and post-op in eyes implanted with an AIOL (r=0.915,p</p>

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<author>James Loughman</author>


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<title>Macular Pigment and its Contribution to Spatial Vision</title>
<link>http://arrow.dit.ie/scschphycon/6</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/6</guid>
<pubDate>Thu, 20 Jan 2011 07:31:51 PST</pubDate>
<description>
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	<p>Purpose:The optical properties and anatomic distribution of macular pigment (MP) are such that it may theoretically contribute to visual performance by attenuating the effects of chromatic aberration and light scatter. The Collaborative Optical Macular Pigment Assessment (COMPASS) study is a placebo-controlled, randomized and double-blind clinical trial designed to assess whether MP optical density (MPOD) influences spatial vision by attenuating short wavelength light. Preliminary analysis of baseline findings, prior to supplementation, is presented here.   Methods:119 young (mean=29+/-6 years) healthy subjects were recruited. The spatial profile of MPOD was assessed by customized heterochromatic flicker photometry. Visual performance was assessed by psychophysical tests including recognition acuity (VA), mesopic contrast sensitivity and photopic contrast sensitivity across spatial frequencies ranging from 1.0 cycles per degree (cpd) to 20.7cpd. Subjects also completed a visual function questionnaire designed to generate a quantitative index of subjects perceived functional performance.   Results:Mean peak MPOD was 0.50+/-0.19. Pearson’s correlation coefficient showed a statistically significant positive relationship between best corrected high contrast VA and MPOD at 0.25, 0.50, 1.0, 1.75, 3.0 degrees of retinal eccentricity and with overall MPOD (r=0.202, p=0.029; r=0.211, p=0.022; r=0.190, p=0.039; r=0.320, p=0.000; r=0.233, p=0.011; r=0.243, p=0.008 respectively). Low contrast VA correlated with central MPOD at 0.25 degrees but at no other retinal eccentricity (r=0.186, p=0.044). The questionnaire derived visual performance index revealed no significant correlation with baseline MPOD. Photopic contrast thresholds exhibited an inverse and statistically significant correlation with MPOD at 0.25, 0.50 and 1.75 degrees of retinal eccentricity but only for the lowest spatial frequency of 1.0 cpd (r=-0.239, p=0.009; r=-0.200, p=0.030; r=-0.230, p=0.012 respectively). Mesopic contrast thresholds showed no statistical correlation with baseline MPOD.   Conclusions:Our results illustrate the difficulties inherent in assessment of MPOD and visual performance using cross sectional, observational methodology. Measures of central visual function including visual acuity and contrast sensitivity reveal variable associations with baseline MPOD. The outcome of this longitudinal, placebo-controlled and randomized supplementation trial will serve to more fully elucidate the potential for visual performance enhancement through MPOD augmentation.</p>

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<author>James Loughman et al.</author>


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<title>The Relationship Between Macular Pigment and Visual Performance</title>
<link>http://arrow.dit.ie/scschphycon/5</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/5</guid>
<pubDate>Thu, 20 Jan 2011 07:31:50 PST</pubDate>
<description>
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	<p>Abstract  Purpose:Macular pigment (MP), as a powerful antioxidant, and short wavelength optical filter, which is anatomically concentrated at the macula, may theoretically contribute to visual performance by attenuating the effects of chromatic aberration and light scatter, or by optimizing retinal health. This study was designed to assess whether macular pigment optical density (MPOD) is associated with visual performance.   Methods:142 young (mean age ± SD = 29 ± 6 years) healthy subjects were recruited into two separate study sites: Waterford Institute of Technology (WIT) and Dublin Institute of Technology (DIT). The spatial profile of MPOD (i.e. at 0.5, 0.25, 1, 1.75 and 3 degrees of retinal eccentricity) was assessed by customized heterochromatic flicker photometry. Visual performance was assessed psychophysically including quantification of best corrected visual acuity (BCVA), mesopic and photopic contrast sensitivity, glare sensitivity, photostress recovery time (PRT) and visual function by self-report.   Results:Mean ± SD peak MPOD (at 0.25°) was 0.48 ± 0.19. There was a positive and statistically significant relationship between BCVA and MPOD across its full spatial profile (r = 0.237 to 0.308, p < 0.01). MPOD was also positively and significantly related to both mesopic and photopic contrast sensitivity (at 7.5 cpd and 11.8 cpd), but this relationship was confined to the central MPOD at 0.25° and 0.50° of retinal eccentricity (r = 0.167 to 0.220, p < 0.05, for all). PRT, glare sensitivity, and self-reported visual function were unrelated to MPOD across its spatial profile.   Conclusions:Measures of central visual function, including visual acuity and contrast sensitivity, are positively associated with MPOD. A longitudinal, placebo-controlled and randomized supplementation trial will be required to ascertain whether augmentation of MP can influence visual performance or experience.</p>

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<author>James Loughman et al.</author>


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<title>Meso-Zeaxanthin Ocular Supplementation Trial in Normals (MOST-N)</title>
<link>http://arrow.dit.ie/scschphycon/4</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/4</guid>
<pubDate>Thu, 20 Jan 2011 07:30:31 PST</pubDate>
<description>
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	<p>Purpose: At the macula, the carotenoids meso-zeaxanthin (MZ), lutein (L) and zeaxanthin (Z) are collectively referred to as macular pigment (MP). To date only one study has reported on MP augmentation following supplementation with MZ, L and Z. However, that study measured only one retinal location (0.75°) and may not have been able to detect changes, if any, at other degrees of retinal eccentricity. Our study was designed to investigate (in a double-blind, randomized placebo controlled fashion) changes in MP optical density (MPOD, including its entire spatial profile), and serum concentrations of the macular carotenoids in response to supplemental MZ, L and Z in healthy subjects.  Methods: We recruited 44 healthy subjects for this study. 22 subjects were randomized to consume a formulation containing 10.6 mg of MZ, 5.9 mg of L and 1.2 mg of Z (Intervention [I] group), and 22 subjects consumed a placebo everyday over a six month period (Pleacebo [P]) group). At each study visit (Baseline [V1], 3 months [V2], and 6 months [V3]) the spatial profile of MPOD (i.e. at 0.25°, 0.5°, 1° and 1.75°) was measured using customised heterochromatic flicker photometry and a blood sample was collected to analyse serum concentrations of L and Z using high performance liquid chromatography.  Results: The mean ± SD age of our subjects was 43.54 ± 12.2. There was a statistically significant increase in serum concentrations of L and Z (μmol/L) and MPOD at 0.25° and 0.5° retinal eccentricity at V2 and V3 in the I group (p 0.05, for all).  Conclusions: Our findings are consistent with previous supplementation studies that have shown increases in serum concentrations of L and Z and MPOD following supplementation with the macular carotenoids. Interestingly, the greatest increase seen in this study was at the centre (0.25°) following supplementation with an MZ dominant formulation.</p>

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<author>James Loughman</author>


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<title>Mozambique Eyecare Programme:A Cross Institutional Collaboration Eliminating Uncorrected Refractive Error In Lusophone Africa</title>
<link>http://arrow.dit.ie/scschphycon/3</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/3</guid>
<pubDate>Thu, 20 Jan 2011 07:16:23 PST</pubDate>
<description>
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	<p>BACKGROUND  This paper will discuss the cross institutional collaboration between governments, higher level institutions, non-governmental organisations and corporations in the Mozambique Eyecare Programme.  OBJECTIVES The aims of this Programme are to collaborate to provide a sustainable solution to the problem of avoidable blindness in developing nations, by addressing the significant barrier of local human resource capacity development, through optometric education, and to enhance specialist knowledge for future collaborations.  METHODS Joint collaboration has developed in the following areas •	Drafting the initial funding proposal to mutually benefit all partners •	Drafting and signing a Memorandum Of Understanding (MOU) to assign responsibilities fairly and realistically •	Disclosing the reporting and management structures within organisations  •	Sharing or developing common materials and resources •	Establishing clear reporting and management structures between partners •	Regular review and analysis of project plan, budget and milestones  RESULTS Successful collaborative efforts within the project include  •	MOU responsibilities respected by the major partners •	Curricular model adapted in line with the Higher Education Reform in Mozambique •	Optometry training clinic plans and build successful, input from the project leaders led to a modern education and retail focussed clinic design  •	Development of research tools and systems through collaborative research workshops  CONCLUSION Cross institutional collaborations work effectively and efficiently to address uncorrected refractive error as a leading cause of global blindness and vision impairment. Roles, responsibilities and clear, realistic, mutually beneficial reporting structures should be agreed upon from project inception.</p>

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<author>Aoife Phelan et al.</author>


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<title>The Mozambique Eyecare Programme – a Partnership which Addresses Avoidable Blindness in Lusophone Africa</title>
<link>http://arrow.dit.ie/scschphycon/2</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/2</guid>
<pubDate>Thu, 20 Jan 2011 06:24:16 PST</pubDate>
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	<p>According to the WHO about 831 million people are visually impaired worldwide, 45 million of them are blind. Most people with visual impairment are older, and females are more at risk at every age, in every part of the world. Uncorrected Refractive Error accounts for over half of all visual impairment. About 87% of the worlds visually impaired live in developing countries.  The Mozambique Eyecare Programme (MEP) is a cross institutional collaboration between governments, higher education institutions, non-governmental organisations and corporations. The aims of this Programme are to collaborate to provide a sustainable solution to the problem of avoidable blindness in developing nations, by addressing the significant barrier of local human resource capacity development, through optometric education, research capacity strengthening and the enhancement of specialist knowledge for future collaborations.  The MEP is an example of how cross institutional collaborations work effectively and efficiently to address uncorrected refractive error as a leading cause of global blindness and vision impairment. Dissemination of lessons learned will inform collaboration with the government and relevant organisations to integrate outcomes into the development of a National Eyecare Plan in Mozambique and other countries.</p>

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<author>Aoife Phelan et al.</author>


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<title>The Significance of Preattentive Visual Search (PAVS) in Glaucoma</title>
<link>http://arrow.dit.ie/scschphycon/1</link>
<guid isPermaLink="true">http://arrow.dit.ie/scschphycon/1</guid>
<pubDate>Thu, 13 Jan 2011 10:45:42 PST</pubDate>
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	<p>The Significance of Preattentive Visual Search (PAVS) in Glaucoma  Methods: A novel test of PAVS, incorporating tests for flicker, motion displacement and orientation, presented on a computer monitor was developed for the detection and monitoring of glaucoma. Patients were required to detect a unique target from a background of 119 distractors. Normality was determined on the basis of patient response times measured using a two-alternative forced choice paradigm. Data were collected on 123 subjects, 41 with existing glaucoma, 41 glaucoma suspects, and 41 age-matched normals.  Results: Paired samples t test indicated a statistically significant difference in PAVS response times between subjects with diagnosed glaucoma, and both glaucoma suspects and normal controls (p < 0.001 for both). More interestingly however, the test also discriminated between suspects and normals (p < 0.01). Test sensitivity and specificity was greater than 90% for all test paradigms. Additional experimental analyses have further demonstrated that the test remains resistant to the potential confounding effects of optical blur, age and target eccentricity.  Discussion: The data support the concept that glaucoma adversely affects preattentive visual search mechanisms (which allow simultaneous analysis of the entire retinal image and therefore presumably requires normal retinal and cortical function).   Conclusion: The battery of tests used allows targeting of both the parvocellular and magnocellular pathways, and thereby may facilitate early detection of glaucoma. The tests are fast, patient friendly, and require only a PC and appropriate software.</p>

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<author>James Loughman et al.</author>


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