Title
Macular Pigment Levels Increase Following Blue-light Filtering Intraocular Lens Implantation
Document Type
Conference Paper
Rights
This item is available under a Creative Commons License for non-commercial use only
Disciplines
3. MEDICAL AND HEALTH SCIENCES
Abstract
Purpose:Photo-oxidative stress is believed to play a role in AMD pathogenesis. Macular pigment (MP), consisting of lutein (L), zeaxanthin (Z) and meso-Z, has a max absorption at 460nm and protects the retina from photo-oxidative injury. We investigated whether the blue light filtering properties of the Alcon AcrySof Natural intraocular lens (ANIOL) implanted during cataract surgery impacts on MP optical density (MPOD). Methods:44 patients scheduled for cataract surgery were recruited. All patients had pre-op best corrected visual acuity (BCVA) of at least 0.5logMAR in the study eye. Patients were randomised to have either the standard Alcon AcrySof 3-piece acrylic intraocular lens (AIOL) or the ANIOL. Spatial profile of MPOD was measured by customised heterochromatic flicker photometry (cHFP) 1 week pre-op and 1 week post-op, and at 3, 6 and 12 months post-op. Serum concentrations of L and Z were measured at each visit. Results:There was a significant positive correlation between MPOD values at 0.25deg recorded 1 week pre- and post-op in eyes implanted with an AIOL (r=0.915,p
Recommended Citation
Nolan, J., O'Reilly, P., Loughman, J., Loane, E., Connolly, E., Stack, J., Beatty, S.: Macular Pigment Levels Increase Following Blue-Light Filtering Intraocular Lens Implantation. Association for Research in Vision and Ophthalmology, ARVO Florida, 2009.
This document is currently not available here.
Publication Details
Association for Research in Vision and Ophthalmology, ARVO Florida, 2009.