Document Type

Article

Rights

This item is available under a Creative Commons License for non-commercial use only

Disciplines

Atomic, Molecular and Chemical Physics

Publication Details

MAGMA, Vol. 25, 4, 2012, p. 263-6

doi: 10.1007/s10334-012-0311-1

Abstract

y

Diffusion-weighted whole-body imaging with background body signal subtraction was introduced as a qualitative approach to detecting metastases in the body. A liver-mimicking phantom with embedded tumours that could be moved to replicate respiratory motion was developed to assess its ability to accurately quantify ADC values.

RESULTS:

Mean tumour ADC values were unaltered by the motion; however, a significant (p < 0.05) increase in the spread of ADC values was measured, even for relatively large tumours.

CONCLUSIONS:

These findings may be of significance in cancer therapy monitoring where subtle changes in ADC histograms may reveal changes in tumour heterogeneity.

DOI

10.1007/s10334-012-0311-1

Included in

Physics Commons

Share

COinS