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Genetics and heredity
187 Irish blood donors were examined for the presence of C282Y and H63D missense mutations using a multiplex PCR and restriction digest protocol. The allele frequency for C282Y was found to be 12.3% which is higher than reported in other studies and concurs that this mutation is of Celtic origin.
Ryan, Fergus and Vaughan, Joseph, "Haemochromatosis mutation analysis in a normal Irish population" (2000). Articles. Paper 46.