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Submissions from 2014

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Ethnic Variation in Breastfeeding and Complementary Feeding in the Republic of Ireland, Patricia Castro, Richard Layte, and John M. Kearney

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Controlled Modifications of Surfaces on the Nanoscale., Ann P. Hopper

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Selection of the Process Parameters for the Mass Plating of Discrete Electronic Components, Ann P. Hopper

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Pilot Data on Brain-to-Blood Efflux of B-Amyloid Peptides in Man, Steve Meaney; Maura Heverin; Ingemar Bjorkhem,; Dorotea Religa; John Wahren; and Ulf Diczfalusy

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Btk Regulated Macrophage Polarization in Response to Lipopolysaccharide, Joan Ní Gabhann, Emily Hams, Siobhán Smith, Claire Wynne, Jennifer C. Byrne, Kiva Brennan, Shaun Spence, and Adrien Kissenpfennig

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Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide, Joan Ní Gabhann, Emily Hams, Siobhán Smith, Claire Wynne, Jennifer C. Byrne, Kiva Brennan, Shaun Spence, Adrien Kissenpfennig, James A. Johnston, Padraic G. Fallon, and Caroline A. Jefferies

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TRIM68 Negatively Regulates IFN-b Production by Degrading TRK Fused Gene, a Novel Driver of IFN-b Downstream of Anti-Viral Detection Systems, Claire Wynne, Elisa Lazzari, Siobhan Smith, Eoghan M. Mc.Carthy, Joan Ni Gabhann, Lara E. Kallai, Rowan Higgs, Sally Ann Cryan, Christine A. Byron, and Caroline A. Jefferies

Submissions from 2013

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Obesity is an Independent Predictor of Breastfeeding Initiation When Socioeconomic Status is Controlled For, Annemarie E. Bennett, Daniel M. McCartney, and John M. Kearney

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Protein Kinase C Delta is a Substrate of Tissue Transglutaminase and a Novel Autoantigen in Coeliac Disease, Greg Byrne, Michael Freeley, Con Feighery, Alex Whelan, and Aideen Long

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Apoptosis is Signalled Early by Low Doses of Ionizing Radiation in a Radiation-Induced Bystander Effect, Hayley Furlong, Carmel Mothersill, Fiona M. Lyng, and Orla Howe

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The relationship between socioeconomic status and nutritional knowledge in women during pregnancy, Michelle Lane, Ellen M. Barrett, Amy C. O'Higgins, Laura E. Mullaney, Michael J. Turner, and Daniel M. McCartney

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Socio-Economic Differences in Food Group and Nutrient Intakes Among Young Women in Ireland, Daniel M. McCartney, Katherine Younger, and John M. Kearney

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Socio-Economic Differences in Food Group and Nutrient Intakes Among Young Women in Ireland, Daniel McCartney, Katherine Younger, Joanne Walsh, Marie O'Neill, Claire Sheridan, and John M. Kearney

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Epigenetic Regulation of Oxysterol Formation, Steve Meaney

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Oxysterols and Parkinson´s Disease. Evidence that Levels of 24S-Hydroxycholesterol in Cerebrospinal Fluid Correlates with the Duration of the Disease., Steve Meaney, Anita Lovgren-Sandblom, Lovisa Brodin, Lisette Salveson, Valerio Leoni, Kristian Winge, Sven Palhagen, and Per Svenninson

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Divergent Mechanisms of Interaction of Helicobacter Pylori and Campylobacter Jejuni with Mucus and Mucins, Julie Ann Naughton; Karina Mariño; Brendan Dolan; Colm Reid; Ronan Gough; Mary Gallagher; Michelle Kilcoyne; Jared GerlachScience,; Lokesh Joshi; Pauline Rudd; Stephen Carrington; Billy Bourke; and Marguerite Clyne

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Mothers Who Formula Feed: Their Practices, Support Needs and Factors Influencing Their Infant Feeding Decision., Roslyn Tarrant

Submissions from 2012

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Weaning Onto Solid foods: Some of the Challenges, Annemarie Bennett, Annalouise O'Connor, Nicola Canning, Alice Kenny, Edel Keaveney, Katherine Younger, and Mary Flynn

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Genetics of SLE: Functional Relevance for Monocytes/Macrophages in Disease, Jennifer C. Byrne, Joan Ní Gabhann, Elisa Lazzari, Rebecca Mahony, Siobhán Smith, Kevin Stacey, Claire Wynne, and Caroline A. Jefferies

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Bi-Lateral Changes to Hippocampal Cholesterol Levels During Epileptogenesis and in Chronic Epilepsy Following Focal-Onset Status Epilepticus in Mice, Steve Meaney, Maura Heverin, Tobias Engel, Eva Jimenez-Mateosa, Reza Al-Aaudia, and David Henshall

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Defects in acute responses to TLR4 in Btk-deficient mice result in impaired dendritic cell-induced IFN-γ production by natural killer cells, Joan Ní Gabhann, Shaun Spence, Claire Wynne, Siobhán Smith, Jennifer C. Byrne, Barbara Coffey, Kevin Stacey, Adrien Kissenpfennig, James A. Johnston, and Caroline A. Jefferies

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Development and Validation of a Novel Reporter Assay for Human Papillomavirus Type 16 Late Gene Expression, Beatrice Orru, Ciaran Cunniffe, Fergus Ryan, and Stefan Schwartz

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Early Formula Feeding Practices and Their Potential Contribution To Later Obesity Risk, Roslyn Tarrant

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The Positive Role of Breastfeeding on Infant Health during the First 6 Weeks: Findings from a Prospective Observational Study Based on Maternal Reports, Roslyn Tarrant, Margaret Sheridan-Pereira, Katherine Younger, and John Kearney

Submissions from 2011

450DNA Methylation Array Analysis of Chronic Lymphocytic Leukaemia Reveals Global Methylation to be Relatively Stable Over Time and Remarkably Similar in Cells Derived From Resting and Proliferative Compartments, Nicola Cahill, Ann-Charlotte Bergh, Hann Goransson-Kultima, Larry Mansouri, Anders Isaksson, Fergus Ryan, Karin Smedby, Gunna Juliusson, Christer Sundstrom, Anders Rosen, and Richard Rosenquist

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Antiviral TRIMs: Friend or Foe in Autoimmune and Autoinflammatory Disease?, Caroline A. Jefferies, Claire Wynne, and Rowan Higgs

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Developing a nutrition assessment tool for Irish pre-schools, Charlotte Johnston Molloy, Clare Corish, John Kearney, Noirin Hayes, and Corina Glennon Slattery

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Protein Replacement Therapy Partially Corrects the Cholesterol-Storage Phenotype in a Mouse Model of Niemann-Pict Type C2 Disease, Gitte Krogh Nielsen, Frederik Dagnaes-Hansen, Ida Elisabeth Holm, Steve Meaney, Derek Symula, Niels Trolle Andersen, and Christian Wurtz Heegaard

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Maternal and Infant Nutritional Supplementation Practices in Ireland: Implications for Clinicians and Policymakers, Roslyn Tarrant, Margaret Sheridan-Pereira, Roberta McCarthy, Katherine Younger, and John Kearney

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Factors Associated with Duration of Breastfeeding in Ireland: Potential Areas for Improvement, Roslyn Tarrant, Katherine Younger, Margaret Sheridan Pereira, and John Kearney

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Maternal Health Behaviours During Pregnancy in an Irish Obstetric Population and Their Assocations with Socio-Demographic and Infant Characteristics, Roslyn Tarrant, Katherine Younger, Margaret Sheridan-Pereira, and John Kearney

Submissions from 2010

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Genetic connections between neurological disorders and cholesterol metabolism, Ingemar Bjorkhem, Valerio Leoni, and Steve Meaney

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Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia., Nicola Cahill and Fergus Ryan

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Release of HMGB1 in response to pro-apoptotic glioma killing strategies: efficacy and neurotoxicity, Marianela Candolfi, Kader Yagiz, David Foulad, Gabrielle E. Alzadeh, Matthew Tesarfreund, AKM Ghulam Muhammad, Mariana Puntel, Kurt M. Kroeger, Chunyan Liu, Sharon Lee, James F. Curtin, Gwendalyn D. King, Jonathan Lerner, Katsuaki Sato, Yohei Mineharu, Weidong Xiong, Pedro R. Lowenstein, and Maria G. Castro

Platelet alpha- and beta- secretase activities are not significantly affected by dementia or mild cognitive impairment in Swedish patients., Paul Gorham, Natalie Bark, Ingemar Bjorkhem, Steve Meaney, and Milita Crisby

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Platelet alpha- and beta- secretase activities are not significantly affected by dementia or mild cognitive impairment in Swedish patients., Paul Gorham, Natalie Bark, Steve Meaney, Ingemar Bjorkhem, and Milita Crisby

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Self Protection from Anti-Viral Responses – Ro52 Promotes Degradation of the Transcription Factor IRF7 Downstream of the Viral Toll-Like Receptors, Rowan Higgs, Elisa Lazzari, Claire Wynne, Joan Ní Gabhann, Alexander Espinosa, Marie Wahren-Herlenius, and Caroline A. Jefferies

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Letter to the Editor, Charlotte Johnston Molloy, Clare Corish, John Kearney, Noirin Hayes, and Corina Glennon Slattery

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Differential genome-wide array–based methylation profiles in prognostic subsets of chronic lymphocytic leukemia, Meena Kanduri, Nicola Cahill, Hanna Göransson, Camilla Enström, Fergus Ryan, Anders Isaksson, and Richard Rosenquist

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Food Consumption Trends and Drivers, John M. Kearney

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A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populations., Lina Keller, Charlotte Murphy, and Steve Meaney

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High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with ‘stereotyped’ IGHV3-21 and IGHV4-34 B-cell receptors, Millaray Marincevic, Nicola Cahill, Rebeqa Gunnarsson, Anders Isaksson, Mahmoud Mansouri, Hanna Göransson, Markus Rasmussen, Mattias Jansson, Fergus Ryan, Karin Karlsson, Hans-Olov Adami, Fred Davi, Jesper Jurlander, Gunnar Juliusson, Kostas Stamatopoulos, and Richard Rosenquist

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An evaluation of MIRU-VNTR analysis and spoligotyping for genotyping ofMycobacterium bovis isolates and a comparison with RFLP typing., Joanne McLernon, Eamonn Costello, Orla Flynn, Gillian Madigan, and Fergus Ryan

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Study of the Efficacy, Biodistribution, and Safety Profile of Therapeutic Gutless Adenovirus Vectors as a Prelude to a Phase I Clinical Trial for Glioblastoma, AKM Ghulam Muhammad, Mariana Puntel, Marianela Candolfi, A Salem, Kader Yagiz, C Farrokhi, Kurt M. Kroeger, Weidong Xiong, James F. Curtin, Chunyan Liu, K Lawrence, Niyati Bondale, Jonathan Lerner, G Baker, David Foulad, Robert Pechnick, Donna Palmer, Philip Ng, Pedro Lowenstein, and Maria Castro

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Factors Associated with Weaning Practices in Term Infants: a Prospective Observational Study in Ireland., Roslyn Tarrant, Katherine Younger, Margaret Sheridan-Pereira, Martin White, and John Kearney

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The Prevalence and Determinants of Breastfeeding Initiation and Duration in a Sample of Women in Ireland, Roslyn Tarrant, Katherine Younger, Margaret Sheridan-Pereira, Martin White, and John Kearney

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An Exploration of the Knowledge and Attitudes Towards Breastfeeding Among a Sample of Chinese Mothers in Ireland, Qianling Zhou, Katherine Younger, and John Kearney

Submissions from 2009

Oxysterols and neurodegenerative diseases, Ingemar Bjorkhem, Angel Cedazo-Minguez, Valerio Leoni, and Steve Meaney

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HMGB1 Mediates Endogenous TLR2 Activation and Brain Tumor Regression, James F. Curtin, Naiyou Liu, Marianela Candolfi, Weidong Xiong, Hikmat Assi, Kader Yagiz, Matthew Edwards, Kathrin Michelsen, Kurt Kroeger, Chunyan Liu, AKM Ghulam Muhammad, Mary Clark, Moshe Arditi, Begonya Comin-Anduix, Antoni Ribas, Pedro R. Lowenstein, and Maria G. Castro

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High-Density Screening Reveals a Different Spectrum of Genomic Aberrations in Chronic Lymphocytic Leukemia Patients with "stereotyped" IGHV3-21 and IGHV4-34 B-Cell Receptors, Millaray Marincevic, Nicola Cahill, Rebeqa Gunnarsson, Anders Isaksson, Mahmoud Mansouri, Mattias Jansson, Fergus Ryan, Karin Karlsson, Hans-Olov Adami, Fred Davi, Jesper Jurlander, Gunnar Juliousson, Kostas Stamatopoulos, and Richard Rosenquist

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An Evaluation of MIRU-VNTR Analysis and Spoligotyping for Genotyping of M. Bovis Isolates and a Comparison with RFLP Typing, Joanne McLernon, Eamon Costello, Orla Flynn, Gillian Madigan, and Fergus Ryan

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Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors., Marjan Shafaati, Riona O'Driscoll, Ingemar Bjorkhem, and Steve Meaney

Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors., Marjan Shafaati, Riona O'Driscoll, Ingemar Bjorkhem, and Steve Meaney

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Adenovirus E4orf4 induces HPV-16 late L1 mRNA production, Monica Somberg, Margaret Rush, Joanna Fay, Fergus Ryan, Helen Lambkin, Göran Akusjärvi, and Stefan Schwartz

Submissions from 2008

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Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials., James F. Curtin, Marianela Candolfi, Tamer Fakhouri, Chunyan Liu, Anderson Alden, Matthew Edwards, Pedro Lowenstein, and Maria Castro

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Regulated Expression of Adenoviral Vectors-Based Gene Therapies: Therapeutic Expression of Toxins and Immune-Modulators, James F. Curtin, Marianela Candolfi, Mariana Puntel, Weidong Xiong, AKM Ghulam Muhammad, Kurt Kroeger, Sonali Mondkar, Chunyan Liu, Niyati Bondale, Pedro Lowenstein, and Maria Castro

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Turning the gene tap off; implications of regulating gene expression for cancer therapeutics, James F. Curtin, Marianela Candolfi, Weidong Xiong, Pedro Lowenstein, and Maria Castro

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Novel functions of acyl-CoA thioesterases and acyltransferases as auxiliary enzymes in peroxisomal lipid metabolism., Mary Hunt and Stefan Alexson

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Book Review J. Mann & A. S. Truswell (editors). Essentials of Human Nutrition., Daniel M. McCartney

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The nudix hydrolase 7 is an acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis., Sarah-Jayne Reilly, Veronica Tillander, Rob Ofman, Stefan E H Alexson, and Mary C. Hunt

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Breastfeeding Practices in Ireland: a Review, Roslyn Tarrant and John Kearney

Submissions from 2007

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Mutagenesis of the Catalytic Triad of Tissue Transglutaminase, Greg Byrne, Fergus Ryan, John Jackson, Con Feighery, and Jacinta Kelly

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Mutagenesis of the catalytic triad of tissue transglutaminase abrogates coeliac disease serum IgA autoantibody binding, Greg Byrne, Fergus Ryan, John Jackson, Con Feighery, and Jacinta Kelly

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Adenoviral Mediated Gene Transfer into the Dog Brain In Vivo, Marianela Candolfi, Kurt Kroeger, Elizabeth Pluhar, Chunyan Liu, Carlos Barcia, Josee Bergeron, Mariana Puntel, James F. Curtin, Elizabeth McNiel, Andrew Freese, John Ohlfest, Peter Moore, William Kuoy, Pedro Lowenstein, and Maria Castro

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The acyl-CoA thioesterase I (Acot1) is regulated by the peroxisome proliferator-activated receptor alpha and hepatocyte nuclear factor 4 alpha via a distal response element in the promotor., Bikesh Dongol, Yatrik Shah, Insook Kim, Frank J. Gonzalez, and Mary Hunt

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Alternative exon usage selectively determines both tissue distribution and subcellular localization of the acyl-CoA thioesterase 7 gene products., Mary Hunt, Sinead Greene, Kjell Hultenby, L. Thomas Svensson, Susanna Engberg, and Stefan E H Alexson

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Human papillomavirus prevalence and genotypes in an opportunistically screened Irish female population, Helen Keegan, Fergus Ryan, Alison Malkin, Mairead Griffin, and Helen Lambkin

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Chlamydia trachomatis detection in cervical PreservCyt specimens from an Irish urban female population, Helen Keegan, Fergus Ryan, Alison Malkin, M. Griffin, and Helen Lambkin

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PPARα is a key regulator of hepatic FGF21, Thomas Lundasen, Mary Hunt, Lisa-Marie Nilsson, Sabysashi Sanyal, Bo Angelin, Stefan Alexson, and Mats Rudling

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A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids., Sarah-Jayne Reilly, Eithne O'Shea, O'Byrne James, Stefan Alexson, and Mary Hunt

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Peroxisomes Contain a Specific Phytanoly-CoA/Pristanoyl-CoA Thioesterase Acting as a Novel Auxiliary Enzyme in Alpha-and Beta-Oxidation of Methyl-Branched Fatty Acids in Mouse, Maria Westin, Mary Hunt, and Stefan Alexson

Submissions from 2006

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In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain, Carlos Barcia, Clare Thomas, James F. Curtin, Gwendalyn King, Kolja Wawrowsky, Marianela Candolfi, Weidong Xiong, Chunyan Liu, Kurt Kroeger, Olivier Boyer, Jerzy Kupiec-Weglinski, David Klatzmann, Maria Castro, and Pedro Lowenstein

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Fms-Like Tyrosine Kinase 3 Ligand Recruits Plasmacytoid Dendritic Cells to the Brain, James F. Curtin, Gwendalyn King, Carlos Barcia, Chunyan Liu, Francois Hubert, Carole Guillonneau, Regis Josien, Ignacio Anegon, Pedro Lowenstein, and Maria Castro

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Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs., Mary Hunt, Anna Rautanen, Maria Westin, Thomas Svensson, and Stefan Alexson

Submissions from 2005

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Endostatin Modulates VEGF-Mediated Barrier Dysfunction in the Retinal Microvascular Endothelium, Brenda Brankin, M. Campbell, P. Canning, T. Gardiner, and A. Stitt

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Development and Validation of a Food-Frequency Questionnaire for the Determination of Detailed Fatty Acid Intakes, Maria Cantwell, Michael Gibney, Denis Cronin, Katherine Younger, John O'Neill, Linda Hogan, and Mary Flynn

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Combining Cytotoxic and Immune-Mediated Gene Therapy to Treat Brain Tumors, James F. Curtin, Gwendalyn King, Marianela Candolfi, Remy Greeno, Kurt Kroeger, Pedro Lowenstein, and Maria Castro

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Gene Therapy and Targeted Toxins for Glioma, James F. Curtin, Gwendalyn King, Marianela Candolfi, Kurt Kroeger, Pedro Lowenstein, and Maria Castro

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Regulatable Gene Expression Systems for Gene Therapy Applications: Progress and Future Challenges, Shyam Goverdhana, Mariana Puntel, Weidong Xiong, Jeffrey Zirger, Carlos Barcia, James F. Curtin, Eric Soffer, Sonali Mondkar, Gwendalyn King, Jinwei Hu, Marianela Candolfi, Diane Greengold, Pedro Lowenstein, and Maria Castro

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New insights into bile acid amidation, Mary Hunt, Eithne O'Shea, Karianne Solaas, Bengt Kase, and Stefan Alexson

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Identification of fatty acid oxidation disorder patients with lowered acyl-CoA thioesterase activity in human skin fibroblasts, Mary Hunt, Jos Ruiter, Petra Mooyer, Carlo W T van Roermond, Rob Ofman, Lodewig Ijlst, and Ronald J A Wanders

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A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases, Mary Hunt, Junji Yamada, Lois Maltais, Mathew Wright, Ernesto Podesta, and Stefan Alexson

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Comparison of DNA extraction from cervical cells collected in PreservCyt solution for the amplification of Chlamydia trachomatis, Helen Keegan, Clara Boland, Alison Malkin, Mairead Griffin, Fergus Ryan, and Helen Lambkin

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Validation of a Multiplex PCR Assay for the Simultaneous Detection of Human Papillomavirus and Chlamydia Trachomatis in Cervical PreservCyt Samples., Helen Keegan, Alison Malkin, Mairead Griffin, Fergus Ryan, and Helen Lambkin

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Real-time reverse transcription PCR for detection and quantitative analysis of equine influenza virus., Michelle Quinlivan, Eugene Dempsey, Fergus Ryan, Sean Arkins, and Ann Cullinnane

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Real-Time Reverse Transcription PCR for Detection and Quantitative Analysis of Equine Influenza Virus, Michelle Quinlivan, Eugene Dempsey, Fergus Ryan, Sean Atkins, and Ann Cullinane

Submissions from 2004

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JNK Regulates HIPK3 Expression and Promotes Resistance to Fas-mediated Apoptosis in DU 145 Prostate Carcinoma Cells, James F. Curtin and Thomas Cotter

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Detection of Five Common CFTR Mutations by Rapid-Cycle Real Time Amplification Refractory Mutation System PCR., Eugene Dempsey, David Barton, and Fergus Ryan

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Detection of Five Common CFTR Mutations by Rapid-Cycle Real-Time Amplification Refractory Mutation System PCR, Eugene Dempsey, Davis Barton, and Fergus X. Ryan

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Assessment of Obesity and Fear of Fatness Among Inner-City Dublin Schoolchildren in a One-Year-Follow-Up Study, Anne Griffin, Katherine Younger, and Mary Flynn

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Increased Frequency of the MTHFR A1298C Mutation in an Irish Population, Cathal McCarthy, Fergus Ryan, and Joseph Vaughan

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Increased frequency of the MTHFR A1298C mutation in an Irish population., Fergus Ryan, Cathal McCarthy, and Joseph Vaughan

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Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARa) regulated peroxisomal acyl-CoA thioesterases., Maria Westin, Mary Hunt, and Stefan Alexson

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Isolation of cancer stem cells from adult glioblastoma multiforme, Xianpeng Yuan, James F. Curtin, Yizhi Xiong, Gentao Liu, Sebastian Waschsmann-Hogiu, Daniel Farkas, Keith Black, and John Yu

Submissions from 2003

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Defects in death-inducing signalling complex formation prevent JNK activation and Fas-mediated apoptosis in DU 145 prostate carcinoma cells, James F. Curtin and Thomas Cotter

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Historical perspectives (Apoptosis), James F. Curtin and Thomas Cotter

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Live and let die: regulatory mechanisms in Fas-mediated apoptosis, James F. Curtin and Thomas Cotter

Submissions from 2002

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Anisomycin activates JNK and sensitises DU 145 prostate carcinoma cells to Fas mediated apoptosis, James F. Curtin and Thomas Cotter

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Regulation and measurement of oxidative stress in apoptosis, James F. Curtin, Maryanne Donovan, and Thomas Cotter

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Characterization of an Acyl-Coa Thioesterase that Functions as a Major Regulator of Peroxisomal Lipid Metabolism, Mary Hunt, Karianne Solaas, Bengt F. Kase, and Stefan E H Alexson