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3. MEDICAL AND HEALTH SCIENCES
We consider the physical nature of the self-diffusion of water molecules in tissue and explore how (Nuclear) Magnetic Resonance (MR) imaging may be used as a means of measuring the rate of diffusion in vivo. A discussion is presented on how these techniques may be implemented as a non-invasive means of assessing the response of tumours to novel therapeutics including some of the basic advantages and disadvan- tages when compared to other methods. The physical basis and mathematical models for diffusion are considered together with models for the distribution of the diffusion co- efficient including a Lévy distributed model. Using a Lévy distributed diffusion model, we develop a novel algorithm for the purpose of improving the signal-to-noise ratio of MR images.
Blackledge, J., Blackledge, M.D.: Magnetic resonance image processing using Levy distributed anisotropic diffusion. 10th International Conference on Environment and Electrical Engineering EEEIC 2011, Rome, 2011