Articles

Novel Tissue Mimicking Materials for High Frequency Breast Ultrasound Phantoms

L. Cannon et al. — Thu, 09 Aug 2012 05:40:09 PDT

The development and acoustical characterisation of a range of novel agar-based tissue mimicking material (TMMs) for use in clinically relevant, quality assurance (QA) and anthropomorphic breast phantoms are presented. The novel agar-based TMMs described in this study are based on a comprehensive, systematic variation of the ingredients in the International Electrotechnical Commission (IEC) TMM. A novel, solid fat-mimicking material was also developed and acoustically characterised. Acoustical characterisation was carried out using an in-house scanning acoustic macroscope at low (7.5 MHz) and high frequencies (20 MHz), using the pulse-echo insertion technique. The speeds of sound range from 1490 to 1570 m. s^-1, attenuation coefficients range from 0.1 to 0.9 dB. cm^‑1. MHz^-1 and relative backscatter ranges from 0 to - 20 dB. It was determined that tissues can be mimicked in terms of independently controllable speeds of sound and attenuation coefficients. These properties make these novel TMMs suitable for use in clinically relevant QA and anthropomorphic phantoms, and would potentially be useful for other high frequency applications such as intra-vascular and small animal imaging.

Review of Ultrasound Elastography Quality Control and Training Test Phantoms

S. Cournane et al. — Mon, 23 Apr 2012 01:30:21 PDT

While the rapid development of ultrasound elastography techniques in recent decades has sparked its prompt implementation in the clinical setting adding new diagnostic information to conventional imaging techniques, questions still remain as to its full potential and efficacy in the hospital environment. A limited number of technical studies have objectively assessed the full capabilities of the different elastography approaches, perhaps due, in part, to the scarcity of suitable tissue-mimicking materials and appropriately designed phantoms available. Few commercially-available elastography phantoms possess the necessary test target characteristics or mechanical properties observed clinically, or indeed reflect the lesion-to-background elasticity ratio encountered during clinical scanning. Thus, while some phantoms may prove useful, they may not fully challenge the capabilities of the different elastography technniques, proving limited when it comes to quality control (QC) and/or training purposes. Although a variety of elastography tissue-mimicking materials, such as agar and gelatine dispersions, co-polymer in oil and poly(vinyl) alcohol cryogel, have been developed for specific research purposes, such work has yet to produce appropriately designed phantoms to adequately challenge the variety of current commercially-available elastography applications. Accordingly, there is a clear need for the further development of elastography TMMs and phantoms to keep pace with the rapid developments in elastography technology, to ensure the performance of these new diagnostic approaches are validated, and for clinical training purposes.

Force Measurement Methods in Telerobotic Surgery: Implications for End-Effector Manufacture

Dean Callaghan et al. — Wed, 07 Oct 2009 10:09:50 PDT

Haptic feedback in telesurgical applications refers to the relaying of position and force information from a remote surgical site to the surgeon in real-time during a surgical procedure. This feedback, coupled with visual information via microscopic cameras, has the potential to provide the surgeon with additional ‘feel’ for the manipulations being performed at the instrument-biological tissue interface. This increased sensitivity has many associated benefits which include, but are not limited to; minimal tissue damage, reduced recuperation periods, and less patient trauma. The inclusion of haptic feedback leads to reduction in surgeon fatigue which contributes to enhanced performance during operation. Commercially available Minimally Invasive Robotic Surgical (MIRS) systems are being widely used, the best-known examples being from the daVinci® by Intuitive Surgical Inc. However, currently these systems do not possess force feedback capability which therefore restricts their use during many delicate and complex procedures. The ideal system would consist of a multi-degree-of-freedom framework which includes end-effector instruments with embedded force sensing included. A force sensing characterisation platform has been developed by this group which facilitates the evaluation of force sensing technologies. Surgical scissors have been chosen as the instrument and biological tissue phantom specimens have been used during testing. This test-bed provides accurate, repeatable measurements of the forces produced at the interface between the tissue and the scissor blades during cutting using conventional sensing technologies. The primary focus of this paper is to provide a review of the traditional and developing force sensing technologies with a view to establishing the most appropriate solution for this application. The impact that an appropriate sensing technology has on the manufacturability of the instrument end-effector is considered. Particular attention is given to the issues of embedding the force sensing transducer into the instrument tip.