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Applied mechanics, Materials engineering, Medical engineering, Cardiac and Cardiovascular systems, Peripheral vascular disease
Atherosclerosis is an ever-increasing cause of morbidity in the western world. Current surgical treatments include bypass grafts and coronary artery stents. However, there is still a need for alternative approaches especially for those who cannot receive conventional therapy. Tissue engineering is one such approach that may hold the key to the repair and regeneration. Tissue engineering is one such approach that may hold the key to the repair and regeneration of coronary arteries. Nevertheless, many questions need to be answered before a vialbe vascular tissie with the inherent properties of native tissue becomes a real contender with the surgical therapies in use today.
Brougham, C., Coughlan, K., Barron, V., McHugh, P.: Mechano-Biological Interactions of Endothelial Cells. Bioengineering In Ireland Conference, January 30-31, 2004, Castle Oaks House Hotel, Castleconnell, Co. Limerick.